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I made the change this week from NetNewsWire (backed by Google Reader for syncing) to the web based Feedly for RSS reading. It's always a little hard to change, but Feedly is good and I'm already pretty used to it. Google Reader closes down on Monday, so if you use an RSS reader that stores your info in Google Reader (many do) you need to change to something else soon. Feedly will import all your subscriptions from Google automatically.